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Diphenidol hydrochloride is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the study of vomiting and vertigo. Diphenidol hydrochloride is also a potent non-specific blocker of voltage-gated ion channels (Na+, K+, and Ca2+) in neuronal cells.
| Molecular Weight | 345.91 |
| Formula | C21H28ClNO |
| CAS Number | 3254-89-5 |
| Solubility (25°C) | DMSO 40 mg/mL Water 15 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related AChR/AChE Products |
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| Biperiden hydrochloride
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