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Dihydrotanshinone-I

Cat. No. M4145

All AbMole products are for research use only, cannot be used for human consumption.

Dihydrotanshinone-I Structure
Size Price Availability Quantity
1mg USD 30 In stock
5mg USD 60 In stock
10mg USD 105 In stock
25mg USD 210 In stock
50mg USD 310 In stock
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Quality Control & Documentation
Biological Activity

Dihydrotanshinone I is a natural product isolated from Salvia miltiorrhiza and widely used in the study of cardiovascular diseases. It is a potent inhibitor of HuR:RNA interaction, active in the low nanomole range, mainly by limiting the binding rate of HuR to RNA.

Chemical Information
Molecular Weight 278.30
Formula C18H14O3
CAS Number 87205-99-0
Solubility (25°C) 10 mM in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xiao-Li Jiang, et al. Dihydrotanshinone I inhibits the growth of hepatoma cells by direct inhibition of Src

[2] Yue Wang, et al. Dihydrotanshinone I inhibits aortic valve interstitial cell calcification via the SMAD1/5/8/NF-κB/ERK pathway

[3] Peipei Luo, et al. Dihydrotanshinone I Is Effective against Drug-Resistant Helicobacter pylori In Vitro and In Vivo

[4] Xiaoping Wang, et al. TFEB-NF-κB inflammatory signaling axis: a novel therapeutic pathway of Dihydrotanshinone I in doxorubicin-induced cardiotoxicity

[5] Zhonglei Bao, et al. Dihydrotanshinone I Increase Amyloid-β Clearance and Decrease Tau Phosphorylation via Enhancing Autophagy

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Keywords: Dihydrotanshinone-I supplier, inhibitors, activators

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