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Difelikefalin (CR-845; FE-202845) TFA

Cat. No. M10432

All AbMole products are for research use only, cannot be used for human consumption.

Difelikefalin (CR-845; FE-202845) TFA Structure
Synonym:

Disomotide; KORSUVA; MR13A9 TFA

Size Price Availability Quantity
1mg USD 150 In stock
5mg USD 310 In stock
10mg USD 500 In stock
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Quality Control & Documentation
Biological Activity

Difelikefalin (CR-845; FE-202845) TFA is a synthetic peptide and the first-in-class, peripherally-restricted, selective agonist of the κ-opioid receptor (KOR) for studies related to pruritus.

Chemical Information
Molecular Weight 793.87
Formula C36H53N7O6.C2HF3O2
CAS Number 1024828-77-0 (free base)
Solubility (25°C) Water 100 mg/mL
DMSO 90 mg/mL
Storage -20°C, dry, sealed
References

[1] Steven Fishbane, et al. Kidney Int Rep. Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Раt iеnts

[2] Steven Fishbane, et al. N Engl J Med. A рhasе 3 Trial of Difelikefalin in Hemodialysis Раt iеnts with Pruritus

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Keywords: Difelikefalin (CR-845; FE-202845) TFA, Disomotide; KORSUVA; MR13A9 TFA supplier, Opioid Receptor, inhibitors, activators

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