Free shipping on all orders over $ 500

Diaziquone

Cat. No. M40729

All AbMole products are for research use only, cannot be used for human consumption.

Diaziquone Structure
Synonym:

AZQ

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Diaziquone is a water-soluble synthetic aziridinyl benzoquinone that selectively alkylates and cross-links DNA, inhibits DNA replication, induces apoptosis, and inhibits the proliferation of tumor cells, with potential antitumor activity.

Chemical Information
Molecular Weight 364.35
Formula C16H20N4O6
CAS Number 57998-68-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] P E Kintzel. Drug Saf. Anticancer drug-induced kidney disorders

[2] S M Devine et al. Semin Oncol. New preparative regimens with diaziquone or cytarabine in combination with busulfan and cyclophosphamide

[3] J F Bender et al. Invest New Drugs. Diaziquone (AZQ)

[4] P L Gutierrez. Drug Metab Rev. The influence of ascorbic acid on the free-radical metabolism of xenobiotics: the example of diaziquone

[5] P L Gutierrez. Free Radic Biol Med. Mechanism(s) of bioreductive activation. The example of diaziquone (AZQ)

Related DNA Alkylator/Crosslinker Products
Apaziquone

Apaziquone is a bioreductive procompound and a chemical analog of the older chemotherapeutic agent mitomycin C.

Bendamustine hydrochloride

Bendamustine hydrochloride is a DNA-alkylator with a distinct pattern of activity.

Dacarbazine

Dacarbazine (DTIC-Dome; DTIC) is an alkylating agent that acts as a purine nucleotide precursor analog to inhibit purine nucleotide synthesis, thereby inhibiting DNA/RNA Synthesis, and can be used in studies related to melanoma and Hodgkin's lymphoma.

Altretamine

Altretamine is an antitumor agent which also acts as a chemosterilant for male houseflies and other insects.

Carmustine

Carmustine is an alkylating antineoplastic agent for inhibiting the growth of U87MG glioblastoma cells with IC50 of 1.42 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Diaziquone, AZQ supplier, DNA Alkylator/Crosslinker, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.