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Desmethylanethol trithione

Cat. No. M20581

All AbMole products are for research use only, cannot be used for human consumption.

Desmethylanethol trithione Structure
Synonym:

ADT-OH; 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1

Size Price Availability Quantity
5mg USD 33 In stock
10mg USD 49 In stock
25mg USD 79 In stock
50mg USD 120 In stock
100mg USD 190 In stock
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Quality Control & Documentation
Biological Activity

Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD.

Chemical Information
Molecular Weight 226.34
Formula C9H6OS3
CAS Number 18274-81-2
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pei Chen, et al. Eur J Med Chem. Design, synthesis, and pharmacological evaluation of the aqueous prodrugs of desmethyl anethole trithione with hepatoprotective activity

[2] A N Masoud, et al. J Chromatogr. Identification and quantitation of a metabolite of anethol dithiolthione in rat and mouse urine using high-performance liquid chromatography

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Keywords: Desmethylanethol trithione, ADT-OH; 5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione; ACS 1 supplier, Apoptosis, inhibitors, activators

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