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Deslorelin is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. It stops the production of sex hormones (testosterone and oestrogen). Unlike other GnRH agonists, which are mainly used to inhibit luteinizing hormone and follicle-stimulating hormone by their ultimate downregulation of the pituitary gland, Deslorelin is primarily used for the initial flare effect upon the pituitary, and its associated surge of LH secretion. After a transient increase, continuous administration of deslorelin results in downregulation of LH and FSH levels followed by a suppression of ovarian and testicular steroid biosynthesis.
| Molecular Weight | 1342.5 |
| Formula | C64H83N17O12.C2H4O2 |
| CAS Number | 57773-65-6 |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related LHRH/GnRH Products |
|---|
| Goserelin acetate
Goserelin acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist. |
| Sufugolix
Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone LHRH receptor antagonist with an IC50 of 0.1 nM. |
| Alarelin Acetate
Alarelin acetate is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. |
| Leuprolide Acetate
Leuprolide acetate is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors. |
| Relugolix
Relugolix, also known as TAK-385, is an orally active gonadotropin-releasing hormone (GnRH) antagonist with an IC50 of 0.12 nM. |
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