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Desisobutyryl-ciclesonide

Cat. No. M13975

All AbMole products are for research use only, cannot be used for human consumption.

Desisobutyryl-ciclesonide Structure
Synonym:

CIC-AP; Ciclesonide active principle

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Quality Control & Documentation
Biological Activity

Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide. Desisobutyryl-ciclesonide has affinity for the glucocorticoid receptor.

Chemical Information
Molecular Weight 470.6
CAS Number 161115-59-9
Solubility (25°C) DMSO ≥ 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jatinder Kaur Mukker, et al. Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids

[2] Deepti Chopra, et al. Ciclesonide--a novel corticosteroid for the management of asthma

[3] Ruediger Nave, et al. Pharmacokinetics of ciclesonide and desisobutyryl ciclesonide after administration via aqueous nasal spray or hydrofluoroalkane nasal aerosol compared with orally inhaled ciclesonide: an open-label, single-dose, three-period crossover study in healthy vol䲧璵Ỵ璶

[4] Neil A Reynolds, et al. Ciclesonide

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Keywords: Desisobutyryl-ciclesonide, CIC-AP; Ciclesonide active principle supplier, GCR, inhibitors, activators

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