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Dehydroepiandrosterone

Cat. No. M9061

All AbMole products are for research use only, cannot be used for human consumption.

Dehydroepiandrosterone Structure
Synonym:

DHEA; Prasterone; Dehydroisoandrosterone

Size Price Availability Quantity
50mg USD 40 In stock
100mg USD 50 In stock
250mg USD 80 In stock
500mg USD 120 In stock
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Quality Control & Documentation
Biological Activity

Dehydroepiandrosterone is an effective antiapoptotic factor, reversing the serum deprivation-induced apoptosis in prostate cancer cells (DU145 and LNCaP cell lines) as well as in colon cancer cells (Caco2 cell line).

In vivo, DHEA in the diet (0.45 % w/w) of male B6 mice (groups of five mice) treated for 8 weeks led to significant decreases in body temperature compared with mice fed the control AIN-76A diet.

Product Citations
Chemical Information
Molecular Weight 288.42
Formula C19H28O2
CAS Number 53-43-0
Solubility (25°C) DMSO 30 mg/mL
Ethanol 20 mg/mL
Storage 10-30°C
References

[1] McNelis JC, et al. Am J Physiol Endocrinol Metab. Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake.

[2] Anagnostopoulou V, et al. Endocrinology. Differential effects of dehydroepiandrosterone and testosterone in prostate and colon cancer cell apoptosis: the role of nerve growth factor (NGF) receptors.

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Keywords: Dehydroepiandrosterone, DHEA; Prasterone; Dehydroisoandrosterone supplier, Animal Modeling, inhibitors, activators

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