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Dehydroepiandrosterone sulfate sodium salt

Cat. No. M14362

All AbMole products are for research use only, cannot be used for human consumption.

Dehydroepiandrosterone sulfate sodium salt Structure
Synonym:

Sodium prasterone sulfate

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Quality Control & Documentation
Biological Activity

Dehydroepiandrosterone sulfate sodium salt (DHEAS) is the most abundant circulating steroid in human. Dehydroepiandrosterone sulfate sodium salt (DHEAS) affects steroid hormone biosynthesis on a molecular level resulting in an increased formation of pregnenolone.

Chemical Information
Molecular Weight 390.47
CAS Number 1099-87-2
Solubility (25°C) DMSO 90 mg/mL
Water 10 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Nursel Muratoğlu Şahin, et al. Vaginal bleeding and a giant ovarian cyst in an infant with 21-hydroxylase deficiency

[2] Dongke Yu, et al. Na +-taurocholate cotransporting polypeptide (NTCP/SLC10A1) ortholog in the marine skate Leucoraja erinacea is not a physiological bile salt transporter

[3] A Purohit, et al. Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate

[4] J E Nestler, et al. Suppression of serum dehydroepiandrosterone sulfate levels by insulin: an evaluation of possible mechanisms

Related Metabolite/Endogenous Metabolite Products
2'-Deoxyinosine

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

Ribitol

Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose.

Glycodeoxycholic Acid

Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

Glycolithocholic acid

Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC).

4-Aminohippuric Acid

4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

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Keywords: Dehydroepiandrosterone sulfate sodium salt, Sodium prasterone sulfate supplier, Metabolite/Endogenous Metabolite, inhibitors, activators

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