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Degarelix acetate is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC50 = 3 nM).
| Molecular Weight | 1692.3 |
| Formula | C82H103ClN18O16.C2H4O2 |
| CAS Number | 934016-19-0 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Laurence Klotz. Drugs Today (Barc). Degarelix acetate for the treatment of prostate cancer
| Related LHRH/GnRH Products |
|---|
| Goserelin acetate
Goserelin acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist), also known as a luteinizing hormone releasing hormone (LHRH) agonist. |
| Deslorelin Acetate
Deslorelin is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. |
| Sufugolix
Sufugolix (TAK-013) is a highly potent and orally available luteinizing hormone-releasing hormone LHRH receptor antagonist with an IC50 of 0.1 nM. |
| Alarelin Acetate
Alarelin acetate is a synthetic GnRH agonist. Alarelin is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. |
| Leuprolide Acetate
Leuprolide acetate is a GnRH analog; leuprolide acetate acts as an agonist at pituitary GnRH receptors. |
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