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Deferiprone is the only orally active iron-chelating agent with an affinity for ferric ion (iron III)，binds with ferric ions to form neutral 3:1 (deferiprone:iron) complexes that are stable over a wide range of pH values. Deferiprone is used therapeutically in conditions of transfusional iron overload.
biochemistry and molecular biology. 2024 May.
MDH2 Promotes Hepatocellular Carcinoma Growth through Ferroptosis Evasion via Stabilizing GPX4
Deferiprone purchased from AbMole
| Molecular Weight | 139.15 |
| Formula | C7H9NO2 |
| CAS Number | 30652-11-0 |
| Solubility (25°C) | DMSO 6 mg/mL Water 3 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Robert C Hider, et al. The Role of Deferiprone in Iron Chelation
[2] Ami Belmont, et al. Deferiprone for the treatment of transfusional iron overload in thalassemia
[3] Sheila A Fisher, et al. Oral deferiprone for iron chelation in people with thalassaemia
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| Erastin
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| Lithocholic acid
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| Idebenone
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