ddUTP

Cat. No. M41241

All AbMole products are for research use only, cannot be used for human consumption.

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Product Information

Biological Activity

ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective HIV and AMV reverse transcriptase inhibitor with Ki values of 0.05 µM and 1 µM, respectively.

Chemical Information

Molecular Weight	452.14
Formula	C9H15N2O13P3
CAS Number	84445-38-5
Storage	Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month

References

[1] David S Baskin et al. Biotechniques. Quantification of DNase type I ends, DNase type II ends, and modified bases using fluorescently labeled ddUTP, terminal deoxynucleotidyl transferase, and formamidopyrimidine-DNA glycosylase

[2] Lorena Gonzalez Palmén et al. J Enzyme Inhib Med Chem. Differential inhibition of homotrimeric dUTPases by the 3'-azido derivative of dideoxy-UTP

[3] L B D'iachenko et al. Mol Biol (Mosk). [Derivatives of ddUTP, modified at the 5-position of uridine, as substrate terminators of reverse transcriptase. Hydrolysis of oligonucleotides, terminated by these analogs, by phosphodiesterase I]

[4] D G Efremov et al. Hemoglobin. Detection of beta-thalassemia mutations by ASO hybridization of PCR amplified DNA with digoxigenin ddUTP labeled oligonucleotides

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ddUTP

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