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DC661

Cat. No. M20648

All AbMole products are for research use only, cannot be used for human consumption.

DC661 Structure
Size Price Availability Quantity
2mg USD 120 In stock
5mg USD 220 In stock
10mg USD 380 In stock
25mg USD 760 In stock
50mg USD 1180 In stock
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Quality Control & Documentation
Biological Activity

DC661 is capable of deacidifying the lysosome and inhibiting autophagy significantly better than hydroxychloroquine (HCQ).

Chemical Information
Molecular Weight 552.58
Formula C31H39Cl2N5
CAS Number 1872387-43-3
Solubility (25°C) DMSO 62 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pengfei Yuan, et al. J Neurochem. Poly (ADP-ribose) polymerase 1-mediated defective mitophagy contributes to painful diabetic neuropathy in the db/db model

[2] Vito W Rebecca, et al. Cancer Discov. PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer

[3] Vaibhav Jain, et al. Cancer Discov. Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition

[4] Gaurav Sharma, et al. JCI Insight. PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma

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Keywords: DC661 supplier, Autophagy, inhibitors, activators

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