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DC-Y13-27, a derivative of DC-Y13, is a YTHDF2 inhibitor (KD = 37.9 μM). DC-Y13-27 enhances tumor responses to radiotherapy and immunotherapy.
Int J Biol Macromol. 2026 Feb 09;348:150816.
YTHDF2 promotes arsenic carcinogenesis through m6A-dependent SMAD7 decay and PRR5 escape from decay
DC-Y13-27 purchased from AbMole
| Molecular Weight | 270.31 |
| Formula | C14H10N2O2S |
| Form | Solid |
| Solubility (25°C) | DMSO 67 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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