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DBIBB is a specific nonlipid agonist of the type 2 G protein coupled receptor for lysophosphatidic acid (LPA2). DBIBB mitigates the gastrointestinal radiation syndrome, increases intestinal crypt survival and enterocyte proliferation, and reduces apoptosis. DBIBB represents a agent candidate capable of mitigating acute radiation syndrome caused by high-dose γ-radiation to the hematopoietic and gastrointestinal system.
| Molecular Weight | 452.48 |
| Formula | C23H20N2O6S |
| CAS Number | 1569309-92-7 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Bibb Allen, et al. J Am Coll Radiol. Democratizing AI
[5] Lorin A Bibb, et al. Cureus. Cyclosporine-induced Erythromelalgia
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