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Dasotraline is a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters with IC50 values of 4, 6, and 11 nM, respectively.
| Molecular Weight | 292.2 |
| Formula | C16H15Cl2N |
| CAS Number | 675126-05-3 |
| Solubility (25°C) | DMSO ≥ 31 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Pankhuree Vandana, et al. Expert Rev Neurother. Dasotraline in ADHD: novel or me too drug?
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Bupropion morpholinol (Hydroxy Bupropion) is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities. |
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