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Dasatinib(BMS-354825) hydrochloride is a potent and dual Abl/ Src inhibitor IC50 of ＜1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM.
| Molecular Weight | 524.47 |
| Formula | C22H27Cl2N7O2S |
| CAS Number | 854001-07-3 |
| Solubility (25°C) | 15 mg/mL in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Cortes JE, et al. Am J Hematol. The impact of dasatinib on pregnancy outcomes.
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