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CYN 154806 TFA is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. CYN 154806 TFA inhibits SRIF-induced increases in extracellular acidification (EAR) in CHO-K1 cells expressing human sst2 receptors (pKB 7.92). CYN 154806 TFA also blocks SRIF-induced increases [35S]-GTPγS binding in CHO-K1 cell membranes expressing human sst2 receptors as well as rat sst2(a) and rat sst2(b) receptors (pKB 7.81, 7.68 and 7.96, respectively).
| Molecular Weight | 1311.36 |
| Formula | C58H69F3N12O16S2 |
| CAS Number | 183658-72-2 (free base) |
| Solubility (25°C) | Water 47 mg/mL |
| Storage | -20°C, sealed |
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