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CYM-5442 is a potent and selective S1P1 agonist with EC50 of 1.35 nM. CYM5442 activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 can easily penetrate the central nervous system (CNS).
Biomaterials. 2024 Dec 10;316:123006.
A supramolecular assembly strategy for the treatment of rheumatoid arthritis with ultrasound-augmented inflammatory microenvironment reprograming
CYM-5442 purchased from AbMole
| Molecular Weight | 409.48 |
| Formula | C23H27N3O4 |
| CAS Number | 1094042-01-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 2 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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| BAF312
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