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CYD-2-11 is a selective Bax agonist with a Ki value of 34.1 nM. CYD-2-11 induces cell apoptosis and shows antiproliferative activity to breast cancer MDA-MB-231 and MCF-7 cell lines with IC50 values of 3.22 and 3.81 μM, respectively. CYD-2-11 suppresses tumor growth in MDA-MB-231 tumor models. CYD-2-11 can be used for the research of breast and lung cancer.
| Molecular Weight | 358.39 |
| Formula | C22H18N2O3 |
| CAS Number | 1425944-22-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Rui Li, et al. Cancer Res. Modulation of Bax and mTOR for Cancer Therapeutics
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