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Cyclovirobuxine D (CVB-D) is the main active ingredient of Buxus microphylla. Cyclovirobuxine D induces autophagy and reduces Akt and mTOR phosphorylation. Cyclovirobuxine D inhibits the proliferation of cancer cells by inhibiting cell cycle progression and inducing mitochondria - mediated apoptosis. Cyclovirobuxine D has the potential to be used in the study of heart failure caused by myocardial infarction.
| Molecular Weight | 402.66 |
| Formula | C26H46N2O |
| CAS Number | 860-79-7 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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