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Cycloastragenol

Cat. No. M11526

All AbMole products are for research use only, cannot be used for human consumption.

Cycloastragenol Structure
Synonym:

Astramembrangenin; Cyclosieversigenin

Size Price Availability Quantity
50mg USD 40 In stock
100mg USD 50 In stock
250mg USD 70 In stock
500mg USD 90 In stock
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Quality Control & Documentation
Biological Activity

Cycloastragenol (Astramembrangenin) is the active form of Astragaloside IV and has antioxidant, anti-inflammatory, anti-aging, anti-apoptotic and cardiovascular protective effects. Cycloastragenol is an effective telomerase activator that lengthens telomeres. Cycloastragenol alleviates age-related bone loss and improves bone microstructure and biomechanical properties.

Chemical Information
Molecular Weight 490.71
Formula C30H50O5
CAS Number 78574-94-4
Form Solid
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Muhammad Ikram, et al. Cells. Cycloastragenol, a Triterpenoid Saponin, Regulates Oxidative Stress, Neurotrophic Dysfunctions, Neuroinflammation and Apoptotic Cell Death in Neurodegenerative Conditions

[2] Jiahuan Wu, et al. Phytother Res. Cycloastragenol protects against glucocorticoid-induced osteogenic differentiation inhibition by activating telomerase

[3] Man Li, et al. Acta Pharmacol Sin. Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia

[4] Chen Chen, et al. Nat Prod Res. Anti-aging derivatives of cycloastragenol produced by biotransformation

[5] Yongjie Yu, et al. Exp Ther Med. Cycloastragenol: An exciting novel candidate for age-associated diseases

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Keywords: Cycloastragenol, Astramembrangenin; Cyclosieversigenin supplier, Telomerase, inhibitors, activators

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