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CVN424 is an orally active and selective GPR6 inverse agonist with a Ki of 9.4 nM and an EC50 of 38 nM. CVN424 can cross the blood-brain barrier and has potential for use in Parkinson's disease research.
| Molecular Weight | 473.52 |
| Formula | C24H29F2N5O3 |
| CAS Number | 2254706-21-1 |
| Solubility (25°C) | DMSO : 62.5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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