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Cucurbitacin B

Cat. No. M4616

All AbMole products are for research use only, cannot be used for human consumption.

Cucurbitacin B Structure
Size Price Availability Quantity
1mg USD 45 In stock
5mg USD 105 In stock
10mg USD 175 In stock
20mg USD 315 In stock
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Quality Control & Documentation
Biological Activity

Cucurbitacin B is a natural compound with anticancer activity. Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest.

Chemical Information
Molecular Weight 558.70
Formula C32H46O8
CAS Number 6199-67-3
Solubility (25°C) DMSO ≥ 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Haoyue Zhang, et al. Cucurbitacin B controls M2 macrophage polarization to suppresses metastasis via targeting JAK-2/STAT3 signalling pathway in colorectal cancer

[2] Putthaporn Kaewmeesri, et al. Cucurbitacin B Diminishes Metastatic Behavior of Cholangiocarcinoma Cells by Suppressing Focal Adhesion Kinase

[3] Hua Luo, et al. Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

[4] Sukant Garg, et al. Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review)

[5] Liangkun You, et al. The role of STAT3 in autophagy

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