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CRT 0105446 (compound 22d) is a LIMK1 inhibitor, with an IC50 of 8 nM.
| Molecular Weight | 421.44 |
| Formula | C20H18F3N3O2S |
| CAS Number | 1661846-05-4 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[1] George Thomas, et al. Arrhythm Electrophysiol Rev. Improving Cardiac Resynchronisation Therapy
[4] M Schlösser, et al. Herzschrittmacherther Elektrophysiol. [Indication for CRT]
| Related LIM Kinase Products |
|---|
| BMS-3
BMS-3 is a potent inhibitor of LIMK1.LIM kinase 1 (LIMK1) activity is essential for cell migration and cell cycle progression. |
| BMS-5
BMS-5 (LIMKi 3) is a potent LIM kinase inhibitor (IC50 values are 7 and 8 nM for LIMK1 and LIMK2 respectively). |
| TH-257
TH-257 is a potent and selective allosteric LIMK 1/2 inhibitor with IC50 values of 84 nM and 39 nM, respectively. |
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Products are for research use only. Not for human use. We do not sell to patients.
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