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Crotonoside

Cat. No. M4646

All AbMole products are for research use only, cannot be used for human consumption.

Crotonoside Structure
Size Price Availability Quantity
5mg USD 35 In stock
10mg USD 60 In stock
20mg USD 90 In stock
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Quality Control & Documentation
Biological Activity

Crotonoside is isolated from Chinese medicinal herb, Croton. Crotonoside inhibits FLT3 and HDAC3/6, exhibits selective inhibition in acute myeloid leukemia (AML) cells. Crotonoside could be a promising new lead compound for the treatment of AML.

Chemical Information
Molecular Weight 283.24
Formula C10H13N5O5
CAS Number 1818-71-9
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fhatuwani Thovhogi, et al. Evaluation of Leaf Mineral, Flavonoid, and Total Phenolic Content in Spider Plant Germplasm

[2] Shih-Chao Lin, et al. Alleviation of Collagen-Induced Arthritis by Crotonoside through Modulation of Dendritic Cell Differentiation and Activation

[3] Zhipei Liu, et al. Antiarrhythmic effect of crotonoside by regulating sodium and calcium channels in rabbit ventricular myocytes

[4] Yu-Zhi Li, et al. Crotonoside exhibits selective post-inhibition effect in AML cells via inhibition of FLT3 and HDAC3/6

[5] Peiao Yan, et al. Pharmacokinetics and tissue distribution of crotonoside

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Keywords: Crotonoside supplier, FLT3, inhibitors, activators

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