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CPPG

Cat. No. M6632

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CPPG Structure
Size Price Availability
5mg USD 330 1-2 Weeks
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Quality Control & Documentation
Biological Activity

CPPG is a potent group II/III mGlu receptor antagonist, with approximately 20-fold selectivity for group III over group II (IC50 values of 2.2 and 46.2 nM respectively). A much less potent antagonist at group I receptors in neonatal rat cortical slices (KB = 0.65 ± 0.07 nM).

Chemical Information
Molecular Weight 271.21
Formula C11H14NO5P
CAS Number 183364-82-1
Solubility (25°C) 1eq. NaOH 27.12 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ai, et al. World J Gastroenterol. Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na3VO4 in rats and its mechanisms.

[2] N J Toms, et al. Br J Pharmacol. The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist

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Keywords: CPPG supplier, GluR, inhibitors, activators

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