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CPI-1189 (REN 1654, REN 1189) is an inhibitor of tumor necrosis factor (TNF) alpha. CPI-1189 inhibits the phosphorylation activation of protein kinase activated by p38 mitogens in cells and plays a neuroprotective role.
| Molecular Weight | 234.29 |
| Formula | C13H18N2O2 |
| CAS Number | 183619-38-7 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 40 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Thomas Mller. Curr Opin Investig Drugs. CPI-1189. Centaur
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