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CP-96345 is a highly potent and selective, orally active tachykinin and substance P receptor non-peptide inhibitor. CP96345 inhibits substance P-induced salivation in the rat by classical in vivo bioassay, but did not inhibit NK2, NK3, or numerous other receptors.
| Molecular Weight | 412.57 |
| Formula | C28H32N2O |
| CAS Number | 132746-60-2 |
| Solubility (25°C) | DMSO 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Neurokinin Receptor Products |
|---|
| Aprepitant
Aprepitant (Emend) is an antiemetic chemical compound that belongs to a class of compounds called substance P antagonists (SPA). |
| Maropitant
Maropitant (Cerenia) is a novel, selective neurokinin type-1 (NK1) receptor antagonist. |
| Eprazinone dihydrochloride
Eprazinone is a mucolytic. |
| Fosaprepitant dimeglumine salt
Fosaprepitant is a water-soluble phosphoryl procompound for Aprepitant which is a NK1 antagonist.*The compound is unstable in solutions, freshly prepared is recommended |
| Netupitant
Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity with Ki of 0.95 nM. |
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