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Compound 25ap

Cat. No. M40998

All AbMole products are for research use only, cannot be used for human consumption.

Compound 25ap Structure

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Quality Control & Documentation
Biological Activity

Compound 25ap is a potent HDAC/JAK/BRD4 triple inhibitor designed based on the novel multi-targeted HDAC inhibitor Fedratinib, which promotes the hyperacetylation of histones and α-microtubulin, hypophosphorylation of STAT3, and down-regulation of LIFR, MCL-1, and c-Myc in MDA-MB-231 cells, and possesses antitumor activity.

Chemical Information
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Chunlong Zhao et al. J Med Chem. Discovery of Novel Fedratinib-Based HDAC/JAK/BRD4 Triple Inhibitors with Remarkable Antitumor Activity against Triple Negative Breast Cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: Compound 25ap supplier, HDAC, inhibitors, activators

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