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Colcemid (Demecolcine) is an effective mitotic inhibitor. Colcemid binds tubulin and blocks cells for metaphase karyotype analysis. Colcemid can induce apoptosis and can be used in tumor research.
| Molecular Weight | 371.43 |
| Formula | C21H25NO5 |
| CAS Number | 477-30-5 |
| Solubility (25°C) | DMSO 25 mg/mL Water 4 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Stefan Florian, et al. Methods Mol Biol. Anti-Microtubule Drugs
[3] T W SHEEHY, et al. AMA Arch Intern Med. Demecolcine (colcemid) toxicity
[5] C L Rieder, et al. J Cell Sci. Colcemid and the mitotic cycle
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