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Cobimetinib hemifumarate is a novel selective MEK1 inhibitor, and the IC50 value against MEK1 is 4.2 nM. In addition, Cobimetinib is an inhibitor of Akt.
| Molecular Weight | 589.25 |
| CAS Number | 1369665-02-0 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | 2-8°C, dry, sealed |
| Related MEK Products |
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AZD6244 (ARRY-142886, Selumetinib) is a potent MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nM. |
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ARRY-162 (MEK-162; Binimetinib) is a selective, potent inhibitor of MEK and cellular pERK with IC50 of 12 nM and 11 nM, respectively. |
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