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CNDAC hydrochloride is a metabolite of Sapacitabine, and it is a nucleoside analog. CNDAC hydrochloride induces DNA damage and apoptosis. CNDAC (20mg/kg; i.p.; daily for 10 days) greatly increased the survival time and survival rate in CDF1 mice P388 tumor model.
| Molecular Weight | 288.69 |
| Formula | C10H13ClN4O4 |
| CAS Number | 134665-72-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage | 4°C, dry, sealed |
| Related Nucleoside Antimetabolite/Analog Products |
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N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. |
| 5-Cyanouridine
5-Cyanouridine is a thymidine analog. |
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| Troxacitabine
Troxacitabine is a nucleoside analog with potent anticancer activity. |
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