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CMLD010509

Cat. No. M29711

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CMLD010509 Structure
Synonym:

SDS-1-021

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Quality Control & Documentation
Biological Activity

CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism.

Chemical Information
Molecular Weight 556.4
Formula C27H26BrNO7
CAS Number 256497-58-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Salomon Manier, et al. Sci Transl Med. Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma

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  Catalog
Abmole Inhibitor Catalog




Keywords: CMLD010509, SDS-1-021 supplier, c-Myc, inhibitors, activators

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