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Clemizole is a H1 histamine receptor antagonist. clemizole hydrochloride can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.clemizole's antiviral effect is moderate (50% effective concentration of 8 microM against an HCV genotype 2a clone). Combinations of clemizole with either interferon, ribavirin, or the nucleoside (NM283) and nonnucleoside (HCV796) HCV polymerase inhibitors were additive.
| Molecular Weight | 325.84 |
| Formula | C19H20ClN3 |
| CAS Number | 442-52-4 |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Histamine Receptor Products |
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