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CL075 (3M002) is a selective TLR8 agonist with immunomodulating properties. CL075 triggers a MyD88-dependent signaling pathway to elicit production of inflammatory cytokines and type I interferons (IFNs) via activation of NF-κB and IRF7, respectively.
| Molecular Weight | 243.33 |
| Formula | C13H13N3S |
| CAS Number | 256922-53-9 |
| Form | Solid |
| Solubility (25°C) | DMSO 22 mg/mL (Need ultrasonic and warming) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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