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CL 316243

Cat. No. M13889

All AbMole products are for research use only, cannot be used for human consumption.

CL 316243 Structure
Synonym:

CL316243

Size Price Availability Quantity
5mg USD 220 In stock
10mg USD 360 In stock
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Quality Control & Documentation
Biological Activity

CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors.CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.

Chemical Information
Molecular Weight 465.79
Formula C20H18ClNNa2O7
CAS Number 138908-40-4
Solubility (25°C) Water ≥ 10 mg/mL
Storage 2-8°C, dry, sealed
References

[1] Melise M Edwards, et al. Effects of Combined Oxytocin and Beta-3 Receptor Agonist (CL 316243) Treatment on Body Weight and Adiposity in Male Diet-Induced Obese Rats

[2] Violeta I Gallardo-Montejano, et al. Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance

[3] Bhagirath Chaurasia, et al. Adipocyte Ceramides Regulate Subcutaneous Adipose Browning, Inflammation, and Metabolism

[4] Tijen Kaya, et al. Effects and selectivity of CL 316243, beta-3-adrenoceptor agonist, in term-pregnant rat myometrium

[5] Yoshitaka Tomiyama, et al. Comparison between CL-316243- and CGP-12177A-induced relaxations in isolated canine ureter

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Keywords: CL 316243, CL316243 supplier, Adrenergic Receptor, inhibitors, activators

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