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CKK-E12 (Liquid)

Cat. No. M22498

All AbMole products are for research use only, cannot be used for human consumption.

CKK-E12 (Liquid) Structure
Synonym:

CKKE12

Size Price Availability Quantity
1mg USD 120 In stock
5mg USD 250 In stock
10mg USD 400 In stock
25mg USD 800 In stock
50mg USD 1280 In stock
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Quality Control & Documentation
Biological Activity

CKK-E12 is a ionizable lipid in combination with other lipids make up the lipid nanoparticles which are used to deliver RNA-based therapeutics. CKK-E12 was highly selective toward liver parenchymal cell in vivo.

Chemical Information
Molecular Weight 993.62
Formula C60H120N4O6
CAS Number 1432494-65-9
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jilian R Melamed, et al. J Control Release. Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery

[2] Yizhou Dong, et al. Proc Natl Acad Sci U S A. Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

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Keywords: CKK-E12 (Liquid), CKKE12 supplier, Liposome, inhibitors, activators

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