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Cipamfylline

Cat. No. M8308

All AbMole products are for research use only, cannot be used for human consumption.

Cipamfylline Structure

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Biological Activity

Cipamfylline is a PDE4 inhibitor that has been shown to cause a cellular redistribution of PDE4A4 into accretion foci, through an association with the ubiquitin scaffolding protein p62.

Chemical Information
Molecular Weight 275.31
Formula C13H17N5O2
CAS Number 132210-43-6
Solubility (25°C) DMSO: ≥10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Helen Nankervis, et al. Scoping systematic review of treatments for eczema

[2] Wolfgang Bumer, et al. Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis

[3] M Kucharekova, et al. The effect of the PDE-4 inhibitor (cipamfylline) in two human models of irritant contact dermatitis

[4] C E M Griffiths, et al. Randomized comparison of the type 4 phosphodiesterase inhibitor cipamfylline cream, cream vehicle and hydrocortisone 17-butyrate cream for the treatment of atopic dermatitis

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Keywords: Cipamfylline supplier, inhibitors, activators

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