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Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro.
| Molecular Weight | 376.94 |
| Formula | C20H25ClN2OS |
| CAS Number | 54-84-2 |
| Form | Solid |
| Solubility (25°C) | DMSO 125 mg/mL (ultrasonic) Water 100 mg/mL (ultrasonic) |
| Storage | 4°C, dry, sealed |
| Related 5-HT Receptor Products |
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| Granisetron hydrochloride
Granisetron hydrochloride is a potent and selective 5-HT3 receptor antagonist that possesses potent antiemetic activity. |
| Sumatriptan succinate
Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache. |
| Vortioxetine hydrobromide
Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro. |
| Prucalopride
Prucalopride is a potent, selective and specific serotonin 5-HT4 receptor agonist with enterokinetic properties. |
| (1S-cis)-Milnacipran Hydrochloride
(1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. |
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