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Cimicoxib

Cat. No. M29756

All AbMole products are for research use only, cannot be used for human consumption.

Cimicoxib Structure
Synonym:

UR-8880

Price and Availability

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Quality Control & Documentation
Biological Activity

Cimicoxib (CX) is an orally active potent and selective COX-2 (cyclo-oxygenase-2) inhibitor. Cimicoxib exhibits promising anti-inflammatory and analgesic activity. The PK parameters of Cimicoxib in dogs given precise (2 mg/kg) and approximate doses (1.95-2.5 mg/kg) are similar.

Chemical Information
Molecular Weight 381.81
Formula C16H13ClFN3O3S
CAS Number 265114-23-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] L A Piras, et al. Res Vet Sci. Post-operative analgesia following TPLO surgery: A comparison between cimicoxib and tramadol

[2] M Schneider, et al. Vet J. Comparative pharmacokinetic profile of cimicoxib in dogs and cats after IV administration

[3] M Schneider, et al. BMC Vet Res. Disposition of cimicoxib in plasma and milk of whelping bitches and in their puppies

[4] Elisabeth C Jeunesse, et al. BMC Vet Res. Pharmacokinetic/pharmacodynamic modeling for the determination of a cimicoxib dosing regimen in the dog

Related COX Products
Firocoxib

Firocoxib is a selective COX-2 inhibitor exhibiting high selectivity to inhibit COX-2.

Celecoxib

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50 values are 15 and 0.04 μM for COX-1 and COX-2 respectively).

Nepafenac

Nepafenac is an analgesic selective inhibitor of COX-2.

Ampiroxicam

Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory compound.

Bromfenac Sodium

Bromfenac is a nonsteroidal anti-inflammatory compound (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

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Abmole Inhibitor Catalog




Keywords: Cimicoxib, UR-8880 supplier, COX, inhibitors, activators

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