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Chromomycin A3 is an aureolic acid-type antitumor antibiotic. Chromomycin A3 forms dimeric complexes with divalent cations, such as Mg2+, which strongly binds to the GC rich sequence of DNA to inhibit DNA replication and transcription.
| Molecular Weight | 1183.25 |
| Formula | C57H82O26 |
| CAS Number | 7059-24-7 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL (ultrasonic) |
| Storage | Powder -20°C |
[2] R H Shafer et al. Eur J Biochem. Chromomycin A3 binds to left-handed poly(dG-m5dC)
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