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CHMFL-BMX-078

Cat. No. M28901

All AbMole products are for research use only, cannot be used for human consumption.

CHMFL-BMX-078 Structure
Synonym:

CHMFL-BMX 078

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Quality Control & Documentation
Biological Activity

CHMFL-BMX-078 is a highly potent and selective type II irreversible BMX kinase inhibitor with an IC50 of 11 nM.

Chemical Information
Molecular Weight 625.67
Formula C33H35N7O6
CAS Number 1808288-51-8
Form Solid
Solubility (25°C) DMSO ≥ 30 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] ShiLong Jiang, et al. Chem Biol Interact. CHMFL-BMX-078, a BMX inhibitor, overcomes the resistance of melanoma to vemurafenib via inhibiting AKT pathway

[2] Xiaofei Liang, et al. J Med Chem. Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)-N-(2-methyl-5-(3,4,5-trimethoxybenzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX)䲧瘀Ỵ瘁㧀痿羹皘

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Keywords: CHMFL-BMX-078, CHMFL-BMX 078 supplier, BTK, inhibitors, activators

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