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Chlorprothixene is a typical antipsychotic compound of the thioxanthene class and was the first of the series to be synthesized. Chlorprothixene exerts strong antagonism at the following receptors: 5-HT2, D1, D2, D3, H1,mACh, α1-adrenergic.
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | B6.129P2 (CF/3)-CftrTgH(neoim)Hgu (abbreviated CFMHH) congenic mice. |
| Formulation | Dissolved in 0.9% NaCl solution, final concentration 8 mg/L |
| Dosages | 1 mL every time |
| Administration | Five 10-minute inhalations, every 12 hours |
| Molecular Weight | 315.86 |
| Formula | C18H18ClNS |
| CAS Number | 113-59-7 |
| Form | Solid |
| Solubility (25°C) | Ethanol 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] Herbert Kferstein, et al. Chlorprothixene in bodies after exhumation
[5] No authors listed. Can J Psychiatr Nurs. Chlorprothixene--Taractan
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