All AbMole products are for research use only, cannot be used for human consumption.
Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent.
Animals and Zoonoses. 2025 Apr 07.
Trichomonas vaginalis inhibits autophagy in VK2/E6E7 cells via the AMPK-ULK1 pathway
Chloroquine diphosphate purchased from AbMole
J Med Virol. 2024 Oct 10;96(10):e29955.
EIF4A3 is stabilized by the long noncoding RNA BC200 to regulate gene expression during Epstein–Barr virus infection
Chloroquine diphosphate purchased from AbMole
Cancer Cell Int. 2024 Sep 28;24(1):327.
CTCF-activated FUCA1 functions as a tumor suppressor by promoting autophagy flux and serum α-L-fucosidase serves as a potential biomarker for prognosis in ccRCC
Chloroquine diphosphate purchased from AbMole
Front Immunol. 2023 Mar 14;14:1120996.
ROS-AMPK/mTOR-dependent enterocyte autophagy is involved in the regulation of Giardia infection-related tight junction protein and nitric oxide levels
Chloroquine diphosphate purchased from AbMole
Oncogene. 2020 Apr;39(15):3163-3178.
The EGFR-ZNF263 Signaling Axis Silences SIX3 in Glioblastoma Epigenetically
Chloroquine diphosphate purchased from AbMole
Int J Neurosci. 2020 Mar 11;1-15.
Autophagy-deficiency in Bone Marrow Mononuclear Cells From Patients With Myasthenia Gravis: A Possible Mechanism of Pathogenesis.
Chloroquine diphosphate purchased from AbMole
 |
Source | International Journal of Neurosci (2020 Mar) Figure 7. chloroquine (Abmole Bioscience Inc., Houston, TX, USA） |
| Method | Apoptosis detection | |
| Cell Lines | BM-MNCs | |
| Concentrations | 0 μM, 2.0 μM, 4.0 μM, 8.0 μM or 16.0 μM | |
| Incubation Time | 48 h | |
| Results | The cell viabilities (means ± SD) of the five 3-MA-treated groups was 100%, 73.13 ± 3.02%, 56.45 ± 2.70%, 34.35 ± 1.65% and 10.14 ± 0.93%, respectively (Figure 7a), while those of the five CHQ-treated groups were 100%, 65.99 ± 3.26%, 48.79 ± 2.51%, 28.04 ± 2.54% and 3.02 ± 0.70%, respectively (Figure 7b). |
| Molecular Weight | 515.86 |
| Formula | C18H26ClN3.2H3O4P |
| CAS Number | 50-63-5 |
| Solubility (25°C) | Water ≥ 30 mg/mL |
| Storage | -20°C, protect from light, sealed |
[2] Yan-Jie Han, et al. Advances and challenges in the prevention and treatment of COVID-19
[3] Thandar Aye, et al. Utility of chloroquine diphosphate in the blood bank laboratory
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