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Chloramphenicol is a first-generation antihistamine compound that is currently being investigated as a potential hepatitis C agent. Chloramphenicol is thought to inhibit early hepatitis C infection by targeting the entry of the virus into host cells. Chloramphenicol inhibited the entry of HCV from cell culture with an IC50 value of 2.3 nM. In human hepatoma cells and primary human hepatocytes, cloclozosin has synergistic effects with other hepatitis C drugs such as ribavirin, interferon, terraprevir, Boceprevir, sofosbuvir, daclatasvir, and cyclosporine A.
| Molecular Weight | 300.83 |
| Formula | C18H21ClN2 |
| CAS Number | 82-93-9 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] No authors listed. Cyclizine
[3] No authors listed. Antiemetic Agents
[5] M C GILL-CAREY. Chlorcyclizine hydrochloride poisoning in an infant
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