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Chloramphenicol palmitate 

Cat. No. M30249

All AbMole products are for research use only, cannot be used for human consumption.

Chloramphenicol palmitate  Structure

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Quality Control & Documentation
Biological Activity

Chloramphenicol palmitate is an orally active broad spectrum antibiotic and has a broad spectrum of activity against gram positive and gram negative bacteria. Chloramphenicol palmitate inhibits bacterial protein synthesis by blocking the peptidyl transferase step. Chloramphenicol palmitate can be used as bacterial selection agent in transformed cells containing chloramphenicol resistance genes.

Chemical Information
Molecular Weight 561.54
Formula C27H42Cl2N2O6
CAS Number 530-43-8
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Siti Nani Nurbaeti, et al. Eur J Pharm Sci. Sustained-release microparticle dry powders of chloramphenicol palmitate or thiamphenicol palmitate prodrugs for lung delivery as aerosols

[2] R E Kauffman, et al. J Pediatr. Relative bioavailability of intravenous chloramphenicol succinate and oral chloramphenicol palmitate in infants and children

[3] D A Powell, et al. Drug Intell Clin Pharm. Chloramphenicol: new perspectives on an old drug

[4] S Shankaran, et al. J Pediatr. Use of chloramphenicol palmitate in neonates

[5] P J Ambrose. Clin Pharmacokinet. Clinical pharmacokinetics of chloramphenicol and chloramphenicol succinate

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