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Chebulic acid

Cat. No. M14987

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Chebulic acid Structure
Size Price Availability Quantity
5mg USD 290 In stock
10mg USD 455 In stock
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Biological Activity

Chebulic acid, a phenolcarboxylic acid compound isolated from Terminalia chebula, has potent anti-oxidant activity, which breaks the cross-links of proteins induced by advanced glycation end-products (AGEs) and inhibits the formation of AGEs. Chebulic acid is effective in controlling elevated metabolic parameters, oxidative stress and renal damage, supporting its beneficial effect in diabetic nephropathy.

Chemical Information
Molecular Weight 356.24
CAS Number 23725-05-5
Solubility (25°C) DMSO 150 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Hai-Yan Zhao, et al. Chebulic acid derivatives from Balakata baccata and their antineuroinflammatory and antioxidant activities

[2] Hyun-Jung Yoo, et al. Chebulic Acid Prevents Methylglyoxal-Induced Mitochondrial Dysfunction in INS-1 Pancreatic β-Cells

[3] Zi-Ni Yang, et al. Isolation, Absolute Configuration, and Biological Activities of Chebulic Acid and Brevifolincarboxylic Acid Derivatives from Euphorbia hirta

[4] Hye-Lim Jung, et al. Protective effects of chebulic acid from Terminalia chebula Retz. against t-BHP-induced oxidative stress by modulations of Nrf2 and its related enzymes in HepG2 cells

[5] Yun-Chang Koo, et al. Chebulic acid prevents hepatic fibrosis induced by advanced glycation end-products in LX-2 cell by modulating Nrf2 translocation via ERK pathway

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