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CGS 9895 is a GABA antagonist that acts via the benzodiazepine binding site of ag containing GABA receptors. CGS 9895 is the only known compound that can specifically enhance GABA-induced currents in ab subunit containing receptors, and acts at the extracellular a1+b3- subunit interface.
| Molecular Weight | 291.3 |
| Formula | C17H13N3O2 |
| CAS Number | 77779-50-1 |
| Solubility (25°C) | DMSO: ≥2 mg/mL (warmed) |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Maria C Maldifassi, et al. Molecular mode of action of CGS 9895 at α1 β2 γ2 GABAA receptors
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