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Cereblon inhibitor 2

Cat. No. M43410

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Cereblon inhibitor 2 Structure

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Biological Activity

Cereblon inhibitor 2 is a Cereblon inhibitor useful in solid tumor research, especially breast cancer.

Chemical Information
Molecular Weight 440.88
Formula C22H21ClN4O4
CAS Number 2639380-62-2
Form Solid
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xingui Liu et al. J Am Chem Soc. Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2

[2] Calla M Olson et al. Nat Chem Biol. Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation

Related E3 Ligase Ligand-Linker Conjugates Products
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Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker.
Thalidomide-O-amido-C4-NH2 (TFA)

Thalidomide-O-amido-C4-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker.
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Keywords: Cereblon inhibitor 2 supplier, E3 Ligase Ligand-Linker Conjugates, inhibitors, activators

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